Are Chondroblastoma Aggressive or Nonaggressive?

In fact, one of the main reasons for recognizing this entity is that clinically it is relatively nonaggressive and readily curable, even more so than ordinary giant cell tumor. Most studies have indicated a close relationship between benign chondroblastoma and chondromyxoid fibroma.

Is chondroblastoma aggressive?

Overall, our findings suggest that chondroblastoma-like osteosarcoma is best considered a low-to-intermediate grade sarcoma with the potential for locally aggressive behavior and late metastases. Chondroblastoma is characterized by the histone H3F3B K36M point mutation in 95% of tumors [17].

Is chondroblastoma malignant?

Chondroblasts are specialized, cartilage-producing cells. Sometimes, these cells can grow out of control and cause a benign (non-cancerous) tumor known as a chondroblastoma.