Are Hydatidiform Mole Hereditary?
Recurrent Hydatidiform Mole Is Inherited in an Autosomal Recessive Pattern, Which Means Both Copies of the Gene in Each Cell Have Mutations. the Parents of an...
Recurrent hydatidiform mole is inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
Do molar pregnancies run in families?
Recurrent molar pregnancy may even be familial, but this is an exceedingly rare condition (2). It is proposed that patients with recurrent hydatidiform moles fall into two groups.
Who is at risk for hydatidiform mole?
The risk of complete molar pregnancy is highest in women over age 35 and younger than 20. The risk is even higher for women over age 45. Age is less likely to be a factor for partial moles. For choriocarcinoma, risk is lower before age 25, and then increases with age until menopause.