Are Mild Involutional Changes in the Brain?

As some people age, the folded brain tissue starts to shrink, making the spaces between the folds (the sulci) deeper and wider. These are called involutional brain changes. In many people with dementia, the folds are greatly shrunken. The involutional changes described in your father's report are milder.

What does white matter on brain MRI mean?

White matter disease is commonly detected on brain MRI of aging individuals as white matter hyperintensities (WMH), or 'leukoaraiosis.” Over the years it has become increasingly clear that the presence and extent of WMH is a radiographic marker of small cerebral vessel disease and an important predictor of the life- ...

What is prominent cerebral sulci?

The grooves or furrows in the brain, called sulci (plural of sulcus), are noticeably widened and there is shrinkage of the gyri (plural of gyrus), the well-developed folds of the brain's outer layer. In addition, the ventricles, or chambers within the brain that contain cerebrospinal fluid, are noticeably enlarged.