Are Ovarian Teratomas Hereditary?

Hecht et al. (1976) suggested that there may be an important genetic factor in ovarian teratomas. They observed affected grandmother and granddaughter and pointed to early onset, bilaterality (in 10 to 25% of patients) and the demonstrable genetic factor in mice (Stevens and Varnum, 1974) as supporting evidence.

Can teratomas be hereditary?

That benign cystic teratomas are heritable is evident on the basis of frequent bilaterality (20%) and early age at onset. Both characteristics suggest genetic tendencies. Indeed, teratomas have been reported in twins, in nontwin siblings, in triplets, in a mother and her two adult daughters, and in three generations.

Do ovarian teratomas come back?

Mature teratomas are usually benign (not cancerous). But they may grow back after being surgically removed.