Are Red Blood Cells Mononucleated?

A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.

What are mononucleated cells?

Mononuclear cells (MNCs) are a mixture of various different types of cells and contain most of the different stem cells within this component of the marrow, but principally contain a number of immature and mature cell types of different myeloid, lymphoid and erythroid lineages.

What type of cells are PBMCs?

PBMCs are blood cells with round nuclei that encompass a heterogeneous cell population comprising various frequencies of lymphocytes (T cells, B cells, and NK cells), dendritic cells, and monocytes (Table 1).