Can Dapsone Cause Liver Damage?

Dapsone induced liver injury can result in acute liver failure, but most cases resolve rapidly with discontinuation of drug and full recovery is expected within 2 to 8 weeks. Severe cholestatic injury may be prolonged.

Can dapsone cause elevated liver enzymes?

Hepatic side effects have frequently included elevations in liver function tests, which may occur as part of the dapsone syndrome. Rare cases of hepatitis and cholestatic jaundice have been reported. Hyperbilirubinemia has also been reported.

What are the long term side effects of taking dapsone?

Rarely, prolonged use of dapsone over months or years at a high dose can lead to impaired function of nerves in the limbs, causing weakness of muscles in the hands and feet.