Can Doxycycline Affect Sleep?

This drug does not cause drowsiness.

Why should you not take doxycycline before bed?

Do not take Doxycycline immediately before going to bed. While you are lying down the pill can reflux back up into the esophagus, where it can irritate or even ulcerate the lining of the esophagus. Take it at least 1 hour before bedtime.

Is insomnia a side effect of antibiotics?

Fluoroquinolones can cause adverse neuropsychiatric side effects, which are more common in older age. We present three cases of levofloxacin-induced acute anxiety and insomnia in young adults. In all the cases, discontinuation of levofloxacin immediately lead to remission.