Can Methergine Cause Prolonged Peripheral Vasoconstriction?

Amphetamine; Dextroamphetamine Salts: (Major) Amphetamines, which increase catecholamine release, can increase blood pressure; this effect may be additive with the prolonged vasoconstriction caused by ergot alkaloids.

Does Methergine cause vasoconstriction?

Methylergonovine maleate produces vasoconstriction and can be expected to reduce the effect of glyceryl trinitrate and other antianginal drugs.

How does Methergine affect blood pressure?

Methergine apparently is more likely to cause the diastolic pressure to rise, while ergonovine seems to affect the systolic pressure more frequently. With both drugs, the blood pressure effect is very rapid, occurring within one minute of administration in most cases.