Can Rifabutin Cause Hypopyon?
Anterior Uveitis and Hypopyon Are the Most Frequent Manifestations of Rifabutin-Associated Uveitis; However, Severe Cases May Develop Dense Vitritis with Large...
Anterior uveitis and hypopyon are the most frequent manifestations of rifabutin-associated uveitis; however, severe cases may develop dense vitritis with large yellow-white opacities or panuveitis resembling endophthalmitis [3, 4].
What causes hypopyon?
Hypopyon is due to accumulation of white blood cells, leading to formation of a thick, white layer in the ventral anterior chamber. Uveitis frequently develops secondary to bacteremia or septicemia and is often observed in neonates with failure of passive transfer.
What drugs can cause uveitis?
These medications include cidofovir, cobalt, diethylcarbamazepine, pamidronic acid (disodium pamidronate), interleukin-3 and interleukin-6, oral contraceptives, quinidine, rifabutin, streptokinase and sulfonamides. Other systemic medications may cause uveitis.
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