Can Setback Be Plural?

The plural form of setback is setbacks.

Is Setback one word or two?

a check to progress; a reverse or defeat: The new law was a setback.

Should setback be hyphenated?

Some need hyphens when they are used as nouns. ... Nouns where the second part is four or more letters are one word: takeover, clampdown, giveaway, setback, lookahead, runaround. Rare exceptions are where two vowels need to be separated by a hyphen, as in go-ahead, though this isn't always necessary.