Can Unexplained Weight Loss Be Normal?

Unexplained weight loss can occur in anyone. However, it is most common (and most serious) in people who are over the age of 65. Even unexplained weight loss of less than 5 percent of body weight or 10 pounds may be the sign of a serious condition in older people.

What tests are done for unexplained weight loss?

Procedures. Endoscopy procedures such as an upper GI endoscopy or colonoscopy can look for evidence of gastrointestinal causes of weight loss. An echocardiogram is an ultrasound of the heart, and it is helpful in diagnosing many conditions, including infections present on the heart valves (infectious endocarditis).

When should I worry about unexplained weight loss?

The point at which unexplained weight loss becomes a medical concern is not exact. But many doctors agree that a medical evaluation is called for if you lose more than 5 percent of your weight in six months to a year, especially if you're an older adult.