Can You Freeze Plasmids?

Plasmids can be stored at -20°C for longer than a year as DNA is quite stable. If your plasmid will undergo numerous freeze-thaw cycles, it will degrade faster. Using a salt-stabilized buffer instead of water will help prevent DNA degradation.

How do you preserve plasmids?

The most common solution is to keep your plasmid at -20°C or even at -80°C, in this case your preparation can be eluted in water or in your buffer of preference, and it will be stable for years.

How long can you store plasmids?

Plasmids provided as DNA, in suspension or on filter paper, should be stored at 4°C for up to two weeks.