Complement Cascade - How to Discuss

Complement cascade

What activates the complement cascade? Additional waterfall. The additional waterfall includes the Classic, Alternative and MBL routes. The classical pathway is activated by the Fc portion of immunoglobulins, which are associated with antigens, apoptotic cells, gram-negative bacteria and viruses. The C1 complex, consisting of the C1q, C1r and C1s subunits, initiates the classical descending cascade.

What is an outcome of the complement cascade?

The complement cascade is a series of reactions in the blood. The cascade activates complement proteins. The result is an attack unit that makes holes in the membrane of bacteria and kills them.