Do All Antipsychotics Cause Agranulocytosis?

Of drugs encountered in psychiatry, antipsychotics including clozapine (risk of agranulocytosis approximately 0.8%, predominantly in the first year of treatment) and phenothiazines (chlorpromazine agranulocytosis risk approximately 0.13%), and antiepileptics (notably carbamazepine, neutropenia risk approximately 0.5%) ...

Which second generation antipsychotic causes agranulocytosis?

Background: Clozapine is known to induce neutropenia as well as agranulocytosis.

Can atypical antipsychotics cause agranulocytosis?

Clozapine is an atypical antipsychotic agent that has several advantages over conventional antipsychotics, not least of which is its superior efficacy. However, the high risk of agranulocytosis (0.8% of patients) associated with clozapine therapy has resulted in restricted indications for its use.