Do All Insulins Need to Be Refrigerated?

According to the product labels from all three U.S. insulin manufacturers, it is recommended that insulin be stored in a refrigerator at approximately 36°F to 46°F. Unopened and stored in this manner, these products maintain potency until the expiration date on the package.

What insulin does not need to be refrigerated?

NovoPen 3, InDuo, and Innovo insulin delivery devices should be stored at room temperature. Unused Novolin PenFill cartridges should be kept in a cold place, preferably in a refrigerator, but not in the freezer compartment. Unused NovoLog and NovoLog Mix 70/30 PenFill cartridges should be kept refrigerated.

What happens if you don't refrigerate insulin?

A: Insulin you are not using should be kept between 36 degrees and 46 degrees Fahrenheit. If it gets colder than that it can freeze. If it gets warmer than that, it will be good for a while, but eventually it will start to break down.