Do Aneuploid Eggs Fertilized?
Errors During Chromosome Segregation in Meiosis Lead to Aneuploid Eggs That Carry an Incorrect Number of Chromosomes [90]. If These Eggs Are Fertilized, They...
Errors during chromosome segregation in meiosis lead to aneuploid eggs that carry an incorrect number of chromosomes [90]. If these eggs are fertilized, they give rise to aneuploid embryos.
Can aneuploid embryos implant?
Moreover, aneuploidy rates are remarkably high in in vitro fertilized human embryos, with up to 50% of embryos diagnosed as aneuploid based on preimplantation genetic testing for aneuploidies (PGT-A)5,6,7. Aneuploidy may lead to implantation failure, miscarriage, as well as congenital defects8.
Can an abnormal egg be fertilized?
Abnormal egg cells typically don't fertilize or implant in the uterus, but in the rare case they do, they can result in miscarriage or genetic disorders like Down syndrome.
James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.
