Do Antidepressants Make You Lose Weight?

Weight changes can be a concern with antidepressants. While more antidepressants typically cause weight gain, a few can reduce appetite, and cause nausea, vomiting, or weight loss. This might be temporary until your body gets used to the medication.

What is the best antidepressant for weight loss?

There are more than a dozen antidepressant drugs that are popularly prescribed. But only one has been consistently associated with weight loss in studies: bupropion (brand name Wellbutrin).

How do antidepressants make you skinny?

Choose low-calorie foods like fresh fruits and vegetables, eat fiber-rich and slow-to-digest complex carbohydrates, and drink lots of water. People taking antidepressants should also be aware of hyponatremia, which is low sodium in the blood.