Do Exotoxins Produce Endotoxins?

Exotoxins may be secreted, or, similar to endotoxins, may be released during lysis of the cell.

How endotoxins are produced?

The endotoxins are produced by Gram negative bacteria of intestinal flora. If the endotoxins are translocated from the intestinal tract to the circulation or injected into bloodstream, they elicit (depending from the quantity of endotoxin), slight or serious effects (e.g. endotoxin shock).

Where are endotoxins produced?

Endotoxins are found in the outer membrane of the cell wall of Gram-negative bacteria. They elicit a strong immune response in man (e.g., fever, septic shock), and cannot be removed from materials by normal sterilization processes.