Do Hydrophobic Molecules Form Hydrogen Bonds?

Hydrophobic groups are not precisely bonded to each other, but rather are held together because of a repulsion from water. They can occur in a non-aqueous environment. They function because hydrophobic groups clump together, so they do not break the hydrogen bonds in the surrounding water.

Are hydrogen bonds hydrophobic?

Nonpolar molecules that repel the water molecules are said to be hydrophobic; molecules forming ionic or a hydrogen bond with the water molecule are said to be hydrophilic.

What molecules are likely to form hydrogen bonds?

Hydrogen bonding occurs only in molecules where hydrogen is covalently bonded to one of three elements: fluorine, oxygen, or nitrogen. These three elements are so electronegative that they withdraw the majority of the electron density in the covalent bond with hydrogen, leaving the H atom very electron-deficient.