Do Injectable Steroids Affect the Liver?

The esterified injectable steroids, including testosterone cypionate and testosterone enanthate, seem to have few adverse effects on the liver and have only rarely been implicated in causing cholestasis (37), but their long-term use may increase the risk of hepatic tumors and nodular transformation (41–45).

Can steroid injections cause liver problems?

Finally, high doses of intravenous corticosteroids, largely methylprednisolone, have been associated with acute liver injury which can result in acute liver failure and death.

Do steroids cause elevated liver enzymes?

Patient monitoring and laboratory tests

Corticosteroids can increase liver enzymes—especially alkaline phosphatase—without inducing liver pathology. Prednisone can increase white blood cell count and decrease lymphocyte count. It can increase serum albumin, glucose, triglycerides, and cholesterol.

Chloe Bennett

Chloe Bennett

Culture, Media & Entertainment Columnist

Chloe Bennett explores the intersection of pop culture, streaming entertainment, digital trends, and contemporary lifestyle. Her weekly commentary reaches thousands of culture enthusiasts.