Do You Have to Dilute Phenobarbital?

Administration: IV direct: undiluted OR diluted to 10mL with sodium chloride 0.9%, dextrose 5% or Ringer's Lactate. Do not administer faster than 50 mg/minute.

How do you administer phenobarbital?

Phenobarbital sodium may be administered intramuscularly or intravenously as an anticonvulsant for emergency use. When administered intravenously, it may require 15 or more minutes before reaching peak concentrations in the brain.

How do you dilute phenobarbital injection?

* Dilute to 100 mg/mL with Sodium Chloride 0.9%. (Withdraw 1 mL of 200 mg/mL solution and add to 1 mL of water for injections in a 2 mL syringe = 200 mg/2 mL = 100 mg/mL). Discard excess volume to obtain required dose or withdraw dose using another syringe.