Does Acetylsalicylic Acid Cause Heartburn?

This is called the number needed to treat, or NNT. However, aspirin therapy has a side effect — it stresses the lining of the stomach and can cause heartburn, gastroesophageal reflux disease, even bleeding.

Is heartburn a side effect of aspirin?

Common aspirin side effects may include: upset stomach, heartburn; drowsiness; or. mild headache.

Can I take aspirin if I have acid reflux?

Taking aspirin with acid reducers can help patients with chronic acid reflux slow the advance of cancer of the esophagus, the tube from the throat to the stomach, a new study has found.