Does Folic Acid Affect Hormones?

Conclusions/Significance. These findings suggest that a diet high in synthetic folate may be associated with increased progesterone levels and lower risk of sporadic anovulation. Further study of the effect of dietary folate and folic acid supplement use on reproductive health is warranted.

Does folic acid change your hormones?

We found that while total folate intake (in dietary equivalents) was not significantly associated with reproductive hormone levels or anovulation, higher intake of dietary synthetic folate was significantly associated with higher luteal progesterone levels and decreased odds of anovulation.

Does folic acid reduce estrogen?

In conclusion, a low folate level is found to be associated with elevated total homocysteine. Folic acid supplementation, either individually or in a combined form with HRT, has a beneficial effect in low estrogen status subsequent to ovariectomy.