Does Nitroglycerin Need to Be Refrigerated

Abstract. Nitroglycerin is a volatile substance which evaporates from tablets if strict precautions are not taken. The tablets kept in small, amber, tightly capped glass bottles in a refrigerator maintain their potency for three to five months if bottles are opened once a week.

How do you store nitroglycerin?

Store the extended-release capsules in a closed container at room temperature, away from heat, moisture, and direct light. Store the sublingual powder at room temperature, away from heat, moisture, and direct light. Sublingual tablets should be kept in the original glass bottle.

Does nitroglycerin lose its potency?

Nitroglycerin rapidly loses potency when stored improperly, compromising effectiveness. Previous studies indicate that patients frequently fail to store nitroglycerin properly. Accordingly, pharmacists routinely advise patients to renew nitroglycerin tablets every 6 months.