Does Protonix Cause Constipation?

It's usual to take pantoprazole once a day in the morning. Common side effects include headaches, constipation or diarrhoea, wind, stomach pain, feeling or being sick. These tend to be mild and go away when you stop taking the medicine.

Can Protonix cause bowel issues?

The high dose of Protonix — not irritable bowel syndrome — is likely the cause of your diarrhea. One of the most serious side effects of proton pump inhibitors (PPI) is C. difficile diarrhea.

Do proton pump inhibitors cause constipation?

PPIs are often the preferred GERD treatment. They can heal the esophageal lining and treat GERD symptoms, but they can cause constipation.