Does Robinul Cross the Blood Brain Barrier

Robinul is chemically a quaternary ammonium compound; hence, its passage across lipid membranes, such as the blood–brain barrier is limited in contrast to atropine sulfate and scopolamine hydrobromide.

Does glycopyrrolate cross the blood brain barrier?

As a quaternary amine, glycopyrrolate is unable to cross the blood–brain barrier and does not exert CNS side effects, but is more potent and longer acting at peripheral muscarinic receptors than atropine.

What drug class is Robinul?

Glycopyrrolate belongs to a class of drugs known as anticholinergics.