Does Taking Thyroxine at Night Affect Sleep?

Conclusions Levothyroxine taken at bedtime significantly improved thyroid hormone levels. Quality-of-life variables and plasma lipid levels showed no significant changes with bedtime vs morning intake. Clinicians should consider prescribing levothyroxine intake at bedtime.

Can thyroid medicine cause sleep problems?

Insomnia. Yes, an underactive thyroid gland can make you feel tired all day, but some of the medications used to treat hypothyroidism may result in insomnia or the inability to fall and stay asleep. Talk to your doctor about your medication including when you take it to see if it's playing a role in your sleeplessness.

Is insomnia a side effect of levothyroxine?

Call your doctor right away if you or your child start to have rapid or irregular heartbeats, chest pain, leg cramps, headaches, nervousness, irritability, sleeplessness, tremors, a change in appetite, weight gain or loss, vomiting, diarrhea, excessive sweating, heat intolerance, a fever, changes in menstrual periods, ...