During Overnight Fasting Blood Glucose Is Maintained by?
The Liver Plays a Major Role in Maintaining Glucose Homeostasis, as It Is the Main Organ for Glucose Storage, in the Form of Glycogen, as Well as Endogenous...
The liver plays a major role in maintaining glucose homeostasis, as it is the main organ for glucose storage, in the form of glycogen, as well as endogenous glucose production. When nutrients are available, insulin is secreted from pancreatic β cells and promotes hepatic glycogen synthesis and lipogenesis.
How is blood glucose maintained during fasting?
Hepatic glucose production, which is primarily regulated by glucagon, maintains basal blood glucose concentrations within a normal range during the fasting state.
How is blood glucose maintained overnight?
The liver manufactures glucose in an unregulated manner all night and consequently the blood glucose level which may have been normal or slightly elevated at bedtime progressively increases overnight and the fasting glucose in the morning is too high (frequently the fasting glucose is the highest glucose of the day).
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