Growth-Promoting Implants for Beef Cattle

Growth-promoting implants offer beef cattle producers a safe and effective way to increase calf weight gains. Implants increase production of muscle tissue and often reduce body fat production. This results in significant improvements in both growth rate and feed efficiency. Despite the proven benefits of implant use, only 11.9 percent of beef cattle operations surveyed by the National Animal Health Monitoring Service (NAHMS) implanted calves before or at weaning.

When used properly, growth-stimulating implants can enhance average daily gain in suckling calves by 4 to 8 percent, in growing calves by 10 to 20 percent, and in finishing cattle by 15 percent. In addition, feed efficiency is expected to improve by 6 to 8 percent in growing cattle and by 8 to 10 percent in finishing cattle.

Adequate nutrition is needed for an implant to enhance calf growth performance. Implants will not make up for poor nutrition. Calf gains must be at least 1.3 pounds per day for implants to be effective at improving growth. Expected return on investment for implant use under proper management is often 10 to 1.

Implants are available for sucking, stockering, and finishing phases of beef cattle production. While implanting may be beneficial for an individual production phase, it is important to consider implant impacts on later production phases, particularly with respect to marketing and retained ownership. Implant effects on quality grade and palatability of the end product must be considered. In some instances, aggressive implanting protocols can reduce quality grade of beef end products. Responsible and strategic implanting programs can make best use of implants while maintaining acceptable end-product quality. For instance, altering the timing of implant administration in relation to harvest can reduce the effects of implanting on quality grade.

Available Implants

The U. S. Food and Drug Administration (FDA) approves and regulates the use of growth-promoting implants for beef cattle. Implants should be administered only in the FDA-approved location in beef cattle, which is between the skin and cartilage in the middle one-third of the backside of the ear.

Implants are typically small pellets impregnated with specific growth promotants. Some implants also contain an antimicrobial, such as oxytetracycline or tylosin tartrate, to provide a local antibacterial effect. Implants are designed for sustained, slow release of the active ingredients and are administered under the skin (subcutaneously) on the backside of the ear midway between the ear tip and base.

Implants can be classified as either estrogenic (hormones affecting female characteristics) or androgenic (hormones affecting male characteristics), based on the specific growth promotants contained in the implants. Estradiol, progesterone, and zeranol are estrogenic. Androgenic implants often contain trenbolate acetate (TBA), which is chemically related to testosterone, alone or in combination with other active ingredients. Using only TBA in the final implant in feedlot cattle may reduce risk of animal health or carcass problems. When more than one implant was used, feedlots surveyed by NAHMS administered an androgenic implant as their final implant to most feedlot cattle.

Table 1. Currently approved implants for sucking beef calves and stocker cattle in the United States.¹

Commercial

Product Name

Marketer

Active Ingredient(s)

Target Animal(s)

Claim

SYNOVEX C

Pfizer Animal Health

100 mg progesterone

10 mg estradiol benzoate

Suckling beef calves up to 400 pounds; steers weighing more than 400 pounds and fed in confinement for slaughter when used as part of a re-implant program in which an initial Synovex C implant is followed at approximately 70 days by Synovex S; not for use in veal calves, calves less than 45 days old, or bull calves intended for reproduction

Increase rate of weight gain

SYNOVEX S

Pfizer Animal Health

200 mg progesterone

20 mg estradiol benzoate

Steers weighing 400 pounds or more; for use in steers only; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

SYNOVEX H

Pfizer Animal Health

200 mg testosterone priopionate

20 mg estradiol benzoate

Nonreplacement heifers weighing 400 pounds or more; for use in heifers only; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

SYNOVEX CHOICE

Pfizer Animal Health

100 mg trenbolate acetate

14 mg estradiol benzoate

Steers fed in confinement for slaughter; for use in calf-fed and yearling feeding programs; not for use in veal calves

Increase rate of weight gain

SYNOVEX Plus

Pfizer Animal Health

200 mg trenbolate acetate

28 mg estradiol benzoate

Steers and heifers fed in confinement for slaughter; not for use in veal calves

Increase rate of weight gain and improve feed efficiency in steers; increase rate of weight gain in heifers

RALGRO

Intervet/

Schering-Plough Animal Health

36 mg zeranol

Suckling beef calves, including replacement heifers between 1 month of age and weaning, weaned beef calves, growing beef cattle, feedlot steers, and feedlot heifers; not for use in breeding herd replacements or lactating dairy cattle

Increase rate of weight gain and improve feed efficiency

RALGRO MAGNUM

Intervet/

Schering-Plough Animal Health

72 mg zeranol

Steers fed in confinement for

slaughter

Increase rate of weight gain and improve feed efficiency

REVALOR-200

Intervet/

Schering-Plough Animal Health

200 mg trenbolate acetate

20 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

REVALOR-G

Intervet/

Schering-Plough Animal Health

40 mg trenbolate acetate

8 mg estradiol

Pasture cattle, including slaughter, stocker, and feeder steers and heifers; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain

REVALOR-H

Intervet/

Schering-Plough Animal Health

140 mg trenbolate acetate

14 mg estradiol

Heifers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

REVALOR-IH

Intervet/

Schering-Plough Animal Health

80 mg trenbolate acetate

8 mg estradiol

Heifers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain

REVALOR-IS

Intervet/

Schering-Plough Animal Health

80 mg trenbolate acetate

16 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

REVALOR-S

Intervet/

Schering-Plough Animal Health

120 trenbolate acetate

24 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

REVALOR-XS

Intervet/

Schering-Plough Animal Health

200 trenbolate acetate

40 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency for up to 200 days

FINAPLIX-H

Intervet/

Schering-Plough Animal Health

200 mg trenbolone

Heifers fed in confinement for slaughter; not for use in breeding herd replacements or lactating dairy cattle; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPUDOSE

Elanco Animal Health

25.7 mg estradiol

0.5 mg oxytetracycline

Suckling and pastured growing steers; finishing steers and heifers; not for use in breeding herd replacements; not for use in veal calves

Increase rate of weight gain in suckling and pastured growing steers; increase rate of weight gain and improve feed efficiency in confined steers and heifers; effective daily dose of estradiol for at least 200 days

ENCORE

Elanco Animal Health

43.9 mg estradiol

0.5 mg oxytetracycline

Suckling and pastured

growing steers; finishing steers and heifers; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain in suckling and pastured growing steers; increase rate of weight gain and improve feed efficiency in confined steers and heifers; effective daily dose of estradiol for at least 400 days

COMPONENT E-C2

Elanco Animal Health

100 mg progesterone USP

10 mg estradiol benzoate

Suckling beef calves up to 400 pounds; not for use in breeding herd replacements; not for use in veal calves, calves less than 45 days old, or bull calves intended for reproduction

Increase rate of weight gain

COMPONENT E-H2

Elanco Animal Health

200 mg testosterone propionate USP

20 mg estradiol benzoate

Heifers weighing 400 pounds or more; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT E-S2

Elanco Animal Health

200 mg progesterone USP

20 mg estradiol benzoate

Steers weighing 400 pounds or more; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT TE-G2

Elanco Animal Health

40 mg trenbolate acetate

8 mg estradiol USP

Pasture cattle including slaughter, stocker, and feeder steers and heifers; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain

COMPONENT TE-H2

Elanco Animal Health

140 mg trenbolate acetate

14 mg estradiol USP

Heifers fed in confinement for slaughter; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT TE-IH2

Elanco Animal Health

80 mg trenbolate acetate

8 mg estradiol

Heifers fed in confinement for slaughter; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain

COMPONENT TE-S2

Elanco Animal Health

120 mg trenbolate acetate

24 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT TE-IS2

Elanco Animal Health

80 mg trenbolate acetate

16 mg estradiol

Steers fed in confinement for slaughter; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT T-H2

Elanco Animal Health

200 mg trenbolate acetate

Feedlot heifers; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

COMPONENT TE-2002

Elanco Animal Health

200 mg trenbolate acetate

20 mg estradiol

Steers and heifers fed in confinement for slaughter; not for use in breeding herd replacements or dairy animals; not for use in veal calves

Increase rate of weight gain and improve feed efficiency

1U.S. Food and Drug Administration approved as of April 2011.
2Available with 29 mg Tylan, tylosin tartrate, as a local antibacterial.

Situations Where Implant Use Is Not Appropriate

As a general rule, do not implant breeding cattle, including bull and replacement heifer calves. Implanting bulls can result in problems in reproductive organ development and sterility. Implanting does not improve growth rate or efficiency in bulls. While some implants are labeled for use in replacement heifers, heifers can develop adequately without implants. It is advisable to implant only heifers to be marketed as feeders or stockers.

Side effects from implant use may include bulling, vaginal and rectal prolapses, udder development, and raised tailheads. Side effects are rare, of little economic significance in most cases, and not a reason to avoid implant use. These situations are often the result of improper implanting technique. Crushed implants may contribute to these conditions.

Some marketing programs specify that no implants be used on cattle in order for cattle to qualify for the programs. For example, “natural” programs may include such implant restrictions. Know the specifics of the targeted marketing program before using implants.

Robert Thorne

Robert Thorne

Automotive & Future Transportation Editor

Robert Thorne covers electric vehicle innovations, autonomous driving systems, global mobility trends, and automotive engineering developments.

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