Has Autophagy Been Proven?

Studies have shown that excessive autophagy may kill cells in the heart, and scientists have linked excessive autophagy to some heart problems. Research has also found that inhibiting autophagy in mice could limit tumor growth and improve responsiveness to cancer treatment.

How long does it take for autophagy to kick in?

Depending on the individual's metabolism, significant autophagy may take two to four days of fasting in humans. Autophagy is believed to begin when glucose and insulin levels drop considerably. Animal studies have shown evidence of autophagy after 24 hours of fasting, which starts peaking at around 48 hours of fasting.

Is autophagy The secret to life extension?

In short, autophagy mostly seems to extend lifespan, but it's possible that in some circumstances autophagy may actually work against one of the body's other anti-aging mechanisms- more research is needed here.