Has No Nucleic Acid?

Prions, so-called because they are proteinaceous, are infectious particles, smaller than viruses, that contain no nucleic acids (neither DNA nor RNA).

Do viroids have nucleic acid?

Although viroids are composed of nucleic acid, they do not code for any protein. The viroid's replication mechanism uses RNA polymerase II, a host cell enzyme normally associated with synthesis of messenger RNA from DNA, which instead catalyzes "rolling circle" synthesis of new RNA using the viroid's RNA as a template.

Where are nucleic acids?

Although first discovered within the nucleus of eukaryotic cells, nucleic acids are now known to be found in all life forms including within bacteria, archaea, mitochondria, chloroplasts, and viruses (There is debate as to whether viruses are living or non-living).