How Accurate Is a Monospot Test

Though the monospot test is considered to be a very specific test, the sensitivity falls in the range of 70 to 90% and is particularly weak among children under the age of four years old.

Can Monospot be wrong?

Antibody Testing False results include: Monospot tests can be false-negative about 10% to 15% of the time, particularly in the early stages of the illness.

Can mono test be false positive?

In rare cases, the test is positive even though you do not have mono. This is called a false-positive result, and it may occur in people with: Hepatitis. Leukemia or lymphoma.