How Are the Antigen Antibody Complexes Detected

Laboratory tests to detect antibodies and antigens outside of the body (e.g., in a test tube) are called in vitro assays. When both antibodies and their corresponding antigens are present in a solution, we can often observe a precipitation reaction in which large complexes (lattices) form and settle out of solution.

Which methodology detects antigen-antibody complexes scatter?

Nephelometry, a method to detect the concentration of serum proteins including immunoglobulin, is based on the concept that particles in solution will scatter light passing through the solution rather than absorbing the light.

How the ouchterlony test detects antigens by using the antigen-antibody reaction?

The Ouchterlony assay demonstrates lattice formation in a gel. The radial immunodiffusion assay is used to quantify antigen by measuring the size of a precipitation zone in a gel infused with antibodies. Insoluble antigens in suspension will form flocculants when bound by antibodies.

Alexander Ross

Alexander Ross

Gaming, Esports & Interactive Media Writer

Alexander Ross has covered the video game industry for a decade, writing deep dives on game design, esports tournaments, VR developments, and gaming culture.

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