How Creatinine Produced in Body?

Creatinine is a non-protein nitrogenous compound that is produced by the breakdown of creatine in muscle. Creatinine is found in serum, plasma, and urine and is excreted by glomerular filtration at a constant rate and in the same concentration as in plasma.

Where does creatinine come from in the body?

Creatinine is a waste product that comes from the normal wear and tear on muscles of the body. Everyone has creatinine in their bloodstream.

What causes increased creatinine?

Generally speaking, high levels of creatinine can indicate that your kidneys aren't working well. There are many possible causes of high creatinine, some of which may be a one-time occurrence. Examples can include things such as dehydration or intake of large amounts of protein or the supplement creatine.