How Do Leydig Cells Produce Testosterone
Leydig Cells Produce Testosterone in the Testes Under the Pulsatile Control of Pituitary Luteinizing Hormone (Lh). cAMP Is the Intracellular Messenger for Lh...
Leydig cells produce testosterone in the testes under the pulsatile control of pituitary luteinizing hormone (LH). cAMP is the intracellular messenger for LH action on steroidogenesis, and pharmacological evidence indicates that the response to LH can be modulated by cyclic nucleotide phosphodiesterases (PDEs).
What stimulates Leydig cells in the testes to produce testosterone?
LH, released from the anterior pituitary, stimulates production of testosterone by the Leydig cell.
Do Leydig cells secrete testosterone?
Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testes. The best-established function of Leydig cells is to produce the androgen, testosterone, under the pulsatile control of pituitary luteinizing hormone (LH) (9).