How Do You Cure Melanosis

There is no treatment for melanosis coli. According to research published in the British Medical Journal, it’s generally reversible within 6 to 12 months after a person stops using anthraquinone-containing laxatives.

What is the cause of Melanosis?

Chronic laxative use, typically from the anthranoid group, causes Melanosis coli. Senna glycoside (Senna) is the main causative laxative. As the laxative travels down the intestinal tract, it remains in its inactive form until it reaches the large intestine.

What causes melanosis coli other than laxatives?

Melanosis coli has also been found in patients who do not use laxatives or suffer from constipation, possibly because of the apoptosis of epithelial cells and their subsequent phagocytosis by macrophages of lamina propria with accumulation of lipofuscin pigment3.