How Does Aldosterone Enter the Cell

Aldosterone enters the principal cells of the distal tubule and the collecting duct of the kidney nephron and then acts on the nuclear mineralocorticoid receptor. This leads to the activation of the basolateral Na+/K+ pumps to pump out 3 Na+ ions out of the cell into the interstitial fluid.

How does aldosterone enter target cells diffusion?

Aldosterone (a steroid hormone) is a small, nonpolar, hydrophobic molecule that enters a target cell by moving across the plasma membrane, down a concentration gradient.

What transport does aldosterone use?

Aldosterone is a type of steroid hormone that acts primarily in renal collecting ducts to stimulate reabsorption of Na+ as well as secretion of K+ and H+. It binds with intracellular receptors in the nucleus that stimulate the expression of several genes.