How Does Aromatization Happen?
Aromatization Occurs When the Aromatase Complex Converts C19 Androgen Substrates to C18 Estrogens in Three Consecutive Reactions: (1) Hydroxylation (2)...
Aromatization occurs when the aromatase complex converts C19 androgen substrates to C18 estrogens in three consecutive reactions: (1) hydroxylation (2) oxidation and (3) demethylation.
What triggers the production of estrogen?
GnRH stimulates the pituitary gland to produce follicle stimulating hormone (FSH), the hormone responsible for starting follicle (egg) development and causing the level of estrogen, the primary female hormone, to rise.
What increases aromatase?
Aromatase activity appears to be enhanced in certain estrogen-dependent local tissue next to breast tissue, endometrial cancer, endometriosis, and uterine fibroids.