How Does D5W Cause Hyponatremia

A brief infusion of 5% dextrose in water (D5W) re-lowers the serum sodium to a more acceptable level, representing a 10-mmol/l increase in 24 h.

How does D5W affect sodium?

A brief infusion of 5% dextrose in water (D5W) re-lowers the serum sodium to a more acceptable level, representing a 10-mmol/l increase in 24 h.

Can dextrose cause hyponatremia?

In at least one of these cases, it is clear that the rapid administration of plain D5W (dextrose 5% in water) postoperatively resulted in acute hyponatremia secondary to free water retention (also called water intoxication, which is described below).