How Does Imipramine Help with Bedwetting?

Tofranil (imipramine) was the first drug introduced to treat bedwetting but we don't know exactly how it works. We do know that it relaxes the bladder muscle, and that it may lighten sleep. The drug benefits the child only on the night taken but doesn't cure the condition.

Can antidepressants help with bedwetting?

Tricyclics are antidepressants, which have been used for treating bedwetting since the 1960s. They probably work by their antispasmodic effect on the bladder.

How can I stop bedwetting permanently?

To combat bed-wetting, doctors suggest:
  1. Shift times for drinking. ...
  2. Schedule bathroom breaks. ...
  3. Be encouraging. ...
  4. Eliminate bladder irritants. ...
  5. Avoid thirst overload. ...
  6. Consider if constipation is a factor. ...
  7. Don't wake children up to urinate. ...
  8. An earlier bedtime.
Marcus Vance

Marcus Vance

Cybersecurity & Digital Privacy Researcher

Marcus Vance is a cybersecurity auditor and technology writer dedicated to educating the public about online safety, data privacy regulations, enterprise security, and emerging cyber threats.