How Does the Pyloric Sphincter Work

The bottom line. The pyloric sphincter is a ring of smooth muscle that connects the stomach and small intestine. It opens and closes to control the passage of partially digested food and stomach juices from the pylorus to the duodenum.

What causes the pyloric sphincter to open?

When there is more acidity in the stomach, the pyloric sphincter opens, and when the acidic contents move into the duodenum, acidity levels rise and cause the sphincter to close immediately.

What relaxes the pyloric sphincter?

Metocloparamide augments the frequency as well as the strength of the contractions of the antral and duodenal muscular wall, synchronizes antral and duodenal contractions (1) and relaxes the pyloric sphincter (2).

James H. Sterling

James H. Sterling

Environmental Science & Climate Journalist

James Sterling reports on renewable energy developments, climate policy, ecological conservation, and green tech innovations around the globe.

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