How Histamine Is Released?
Histamine Is Released from Cells in Response to an Antibody Called Immunoglobulin E (Ige). This Antibody May Be Secreted in Response to an Invading Pathogen...
Histamine is released from cells in response to an antibody called immunoglobulin E (IgE). This antibody may be secreted in response to an invading pathogen such as a virus, bacteria, or an allergenic substance such as pollen. Histamine can also be released in response to injury caused by toxins.
What causes histamine to be released?
In an allergic reaction—the immune system's hypersensitivity reaction to usually harmless foreign substances (called antigens in this context) that enter the body—mast cells release histamine in inordinate amounts.
What happens when histamine is released?
Effects of histamine
Histamine is released at the mucosal surfaces as a result of exposure to foreign particles. This histamine release causes the capillaries to become more permeable to white blood cells, which move into the capillaries and proceed to target and attack foreign bodies in the affected tissue.
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