How Is Cocaethylene Formed
Cocaethylene (Ethylbenzoylecgonine) Is the Ethyl Ester of Benzoylecgonine. It Is Structurally Similar to Cocaine, Which Is the Methyl Ester of Benzoylecgonine...
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine. It is structurally similar to cocaine, which is the methyl ester of benzoylecgonine. Cocaethylene is formed by the liver when cocaine and ethanol coexist in the blood.
Is Cocaethylene an active metabolite?
Cocaethylene is an active metabolite responsible for life-threatening toxicity if cocaine and alcohol are abused simultaneously.
What's the half life of Cocaethylene?
The median half-life of cocaethylene was 144.3 minutes whereas the median half-life of cocaine was 96.7 minutes (p < 0.01).