How Is Globin Formed

The combination of two alpha genes and two gamma genes forms fetal hemoglobin, or hemoglobin F. Around the time of birth, the production of gamma globin declines in concert with a rise in beta globin synthesis. A significant amount of fetal hemoglobin persists for seven or eight months after birth.

What makes up the globin part of hemoglobin?

Human hemoglobin, the most widely studied of all of the globin proteins, is composed of two alpha-like globin chains, two beta-like globin chains, and four heme moieties. The heme groups contain iron atoms which allow hemoglobin to transport oxygen from the lungs to the tissues [3].

What is alpha globin made of?

Alpha-globin is a component (subunit) of a larger protein called hemoglobin, which is the protein in red blood cells that carries oxygen to cells and tissues throughout the body. Hemoglobin is made up of four subunits: two subunits of alpha-globin and two subunits of another type of globin.