How Is Parathyroid Adenoma Different from Hyperplasia

In hyperplasia all four parathyroid glands are affected although they are not necessarily enlarged. In adenoma usually only one gland is affected while the other parathyroid glands may become atrophic. Parathyroid carcinoma is rare.

What is the difference between adenoma and hyperplasia?

An adenoma consists of one enlarged gland, which sometimes has a compressed rim of normal parathyroid tissue. It is also necessary to have at least one biopsy-proven additional normal gland. Hyperplasia involves multiple glands.

What causes hyperplasia of the parathyroid gland?

The most common conditions that can cause parathyroid hyperplasia are chronic kidney disease and chronic vitamin D deficiency. In both cases, the parathyroid glands become enlarged because vitamin D and calcium levels are too low.

Sarah Jenkins

Sarah Jenkins

Senior Technology Editor & AI Specialist

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.

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