How Is Procainamide Given

Procainamide is given IV or PO with the onset of action in 10 to 30 minutes. The loading dose is of IV procainamide is 10 to 17 mg/kg and administered at a rate of 20 to 50 mg/min. Alternatively, this may be dosed at 100 mg every 5 minutes in adult patients.

When is procainamide given?

Immediate-acting procainamide usually is taken every 3 or 4 hours. The long-acting product is usually taken every 6 or 12 hours.

How do you make a procainamide infusion?

Intravenous Administration Each 100 mg of procainamide must be diluted in 10 ml of sterile water for injection or D5W injection. Inject by slow IV push at a rate not to exceed 50 mg/minute. Intravenous infusion: NOTE: According to the manufacturer, procainamide injection is compatible in D5W.