How Long Does Oritavancin Last

Based on population kinetics, the half-life of oritavancin is 393 hours, allowing for a single-dose strategy.

How is oritavancin eliminated?

Oritavancin’s antimicrobial activity is reduced when vancomycin activity is reduced, with minimum inhibitory concentration of 90% (MIC90) of 1 µg/mL and 2 µg/mL for VRSA and VISA, respectively [14]. This difference was not due to adherence, as polysorbate 80 was included in the in vitro testing as described below.

What is oritavancin used to treat?

Oritavancin injection is used to treat acute bacterial skin and skin structure infections (ABSSSI). Oritavancin belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. Oritavancin will not work for colds, flu, or other virus infections.