How Macula Densa Work?
Macula Densa Cells Sense Changes in Sodium Chloride Level, and Will Trigger an Autoregulatory Response to Increase or Decrease Reabsorption of Ions and Water...
Macula densa cells sense changes in sodium chloride level, and will trigger an autoregulatory response to increase or decrease reabsorption of ions and water to the blood (as needed) in order to alter blood volume and return blood pressure to normal.
What is the function of the macula densa?
Macula densa (MD) cells are chief cells within the kidney, playing key sensory and regulatory functions in the maintenance of body fluid, electrolyte homeostasis, and blood pressure.
How does macula densa release renin?
Macula-Densa Control of Renin Release
The macula densa participates in the regulation of renin release from juxtaglomerular granular cells. Renin secretion depends on NaCl delivery to and reabsorption by the macula-densa cells at the end of the TAL.
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