How Many Schistocytes in Ttp?

A schistocyte count greater than 1% appears to be diagnostic of TTP in the appropriate clinical setting. 20 Burns et al. possibility that some patients with TTP may have fewer than 1% schistocytes on presentation.

Does TTP have schistocytes?

The presence of schistocytes on the peripheral blood smear is a characteristic laboratory finding of TTP (Fig. 134.4). Schistocytes may not be apparent in rare patients at disease onset. The markedly elevated levels of plasma LDH typically seen in patients with TTP reflect both hemolysis and tissue ischemia.

How many schistocytes are in a high power field?

Two (2) schistocytes per HPF correlated with 1% schistocytes on the linear plot. At UCMC, policy had been to report 2-8 schistocytes per HPF as present and >8 per HPF as increased. These findings indicated that the threshold for reporting increased schistocytes should be lowered from >8 per HPF to >2 per HPF.