How Often Does Hurler Syndrome Occur?

Incidence. Globally, severe MPS I occurs in about 1 in every 100,000 births and is divided into three groups according to the type, severity, and the way the symptoms progress. Attenuated MPS I is less common, occurring in less than 1 in 500,000 births.

How common is Hurler syndrome?

The incidence of Hurler syndrome is approximately 1 in 100,000 births.

How does Hurler syndrome occur?

Hurler syndrome is an inherited condition caused by a faulty gene. Children with Hurler syndrome lack an enzyme that the body needs to digest sugar. As a result, undigested sugar molecules build up in the body, causing progressive damage to the brain, heart, and other organs.